OrderlyMeds vs ShedRx vs SkinnyRx (2026)

On tirzepatide, the order is ShedRx↗ ($289) → SkinnyRx↗ ($299) → OrderlyMeds↗ ($299) — gaps of $10 and then $0 a month, a $120 spread across a year between first and last. All-in figures, 10 mg basis, captured 2026-08-09.

Updated 2026-08-10 · figures captured 2026-08-09 · how we verify

§ Each record, condensed

The three records, one screen

ShedRx: the record, condensed

On tirzepatide, the number that matters at ShedRx is $289 a month all-in — the figure at the 10 mg maintenance basis this whole site ranks on. Pricing steps with the dose here: from $199 at entry to $289 at the 10 mg basis. Multiply the wrong one of those by twelve and your budget is off by $1,080 a year, which is why every ranking on this site uses the larger number.

The absence worth noticing: no mandatory membership. Across this index memberships run $25–$145 a month and hide outside headline prices; here the headline is the bill.

To place the number: #5 of 17 verified programs, with the floor $74/month below at NexLife↗ ($215); the approved-product yardstick (Zepbound (LillyDirect↗)) sits at $449, so the compounded case here is worth $160 a month. A year at this figure: $3,468 monthly-billed.

Start with the load-bearing figure: $249 a month, all-in, is what ShedRx charges for semaglutide at the 2.4 mg basis. The structure is tiered: the advertised entry point is $175, but the maintenance figure — the one a full year is actually billed at — is $249. That $74 gap between the ad and the anniversary is the single most important line in this record.

Nothing recurs on top: no membership, no platform fee, no “provider access” line. The $249 is the whole subscription, which makes ShedRx unusually easy to compare and unusually easy to leave.

Context for that figure: it ranks #13 of 20 in the verified semaglutide index — $116/month above the floor (Oak Longevity, $133) — and sits $100 under the brand benchmark (Wegovy (NovoCare↗), $349 at maintenance). Annualized, a monthly-billed year here runs $2,988.

Operationally at ShedRx: shipping included; commitment none month-to-month; cancellation 72-hour notice before the next billing cycle; pharmacy not publicly named — ask in writing before paying; states: not published; evidence source-verified, captured 2026-08-05. The full record with source and archive links: the ShedRx page · visit ShedRx ↗

SkinnyRx: the record, condensed

Start with the load-bearing figure: $299 a month, all-in, is what SkinnyRx charges for tirzepatide at the 10 mg basis. Because pricing is flat across the ladder (2.5 → 5 → 7.5 → 10 mg (12.5 and 15 mg available)), a dose increase at SkinnyRx is a clinical event and not a billing one. Whatever your prescriber decides, the invoice does not move, which makes this one of the few programs whose headline figure you can actually plan a year around.

There is no membership line. $299 is the billed total — consultation and clinical review are inside it, and no platform fee recurs beside it, which removes the most common way advertised GLP-1 prices understate billed ones.

To place the number: #7 of 17 verified programs, with the floor $84/month below at NexLife ($215); the approved-product yardstick (Zepbound (LillyDirect)) sits at $449, so the compounded case here is worth $150 a month. A year at this figure: $3,588 monthly-billed.

On semaglutide, the number that matters at SkinnyRx is $199 a month all-in — the figure at the 2.4 mg maintenance basis this whole site ranks on. The price is dose-flat: the standard titration ladder (0.25 → 0.5 → 1.0 → 1.7 → 2.4 mg) is financially invisible here, because the top rung bills exactly what the bottom rung billed. That converts the advertised number from a floor into a ceiling — the strongest single structural feature a program in this category can have.

There is no membership line. $199 is the billed total — consultation and clinical review are inside it, and no platform fee recurs beside it, which removes the most common way advertised GLP-1 prices understate billed ones.

Context for that figure: it ranks #11 of 20 in the verified semaglutide index — $66/month above the floor (Oak Longevity, $133) — and sits $150 under the brand benchmark (Wegovy (NovoCare), $349 at maintenance). Annualized, a monthly-billed year here runs $2,388.

Operationally at SkinnyRx: shipping included; commitment none; cancellation no membership on compounded programs; pharmacy not publicly named — ask in writing before paying; states: not published; evidence source-verified, captured 2026-08-05. The full record with source and archive links: the SkinnyRx page · visit SkinnyRx ↗

OrderlyMeds: the record, condensed

OrderlyMeds’s tirzepatide program bills $299 a month once every mandatory fee is counted, measured at the 10 mg maintenance basis. The price is dose-flat: the standard titration ladder (2.5 → 5 → 7.5 → 10 mg (12.5 and 15 mg available)) is financially invisible here, because the top rung bills exactly what the bottom rung billed. That converts the advertised number from a floor into a ceiling — the strongest single structural feature a program in this category can have.

Nothing recurs on top: no membership, no platform fee, no “provider access” line. The $299 is the whole subscription, which makes OrderlyMeds unusually easy to compare and unusually easy to leave.

To place the number: #8 of 17 verified programs, with the floor $84/month below at NexLife ($215); the approved-product yardstick (Zepbound (LillyDirect)) sits at $449, so the compounded case here is worth $150 a month. A year at this figure: $3,588 monthly-billed.

OrderlyMeds’s semaglutide program bills $149 a month once every mandatory fee is counted, measured at the 2.4 mg maintenance basis. Because pricing is flat across the ladder (0.25 → 0.5 → 1.0 → 1.7 → 2.4 mg), a dose increase at OrderlyMeds is a clinical event and not a billing one. Whatever your prescriber decides, the invoice does not move, which makes this one of the few programs whose headline figure you can actually plan a year around.

Nothing recurs on top: no membership, no platform fee, no “provider access” line. The $149 is the whole subscription, which makes OrderlyMeds unusually easy to compare and unusually easy to leave.

Context for that figure: it ranks #4 of 20 in the verified semaglutide index — $16/month above the floor (Oak Longevity, $133) — and sits $200 under the brand benchmark (Wegovy (NovoCare), $349 at maintenance). Annualized, a monthly-billed year here runs $1,788.

Operationally at OrderlyMeds: shipping included; commitment none stated; cancellation not published; pharmacy not publicly named — ask in writing before paying; states: not published; evidence no public price, captured 2026-08-05. The full record with source and archive links: the OrderlyMeds page · visit OrderlyMeds ↗

§ The three-way read

Prices, gaps, and what sits inside them

ShedRx holds the low ground at $289 with no membership attached. SkinnyRx follows at $299 (+$10/mo, $120/yr). OrderlyMeds tops the trio at $299 (+$10/mo over the leader, $120/yr) — note its record’s watch-out below.

The semaglutide picture reshuffles the order: OrderlyMeds $149 → SkinnyRx $199 → ShedRx $249 — a reminder that molecule choice and provider choice are separate decisions, priced separately in the semaglutide index.

§ Category winners among the three

Who wins what

Cheapest month-to-month: ShedRx ($289); cheapest 12-month path: ShedRx ($3,468); dose-flat structure: SkinnyRx and OrderlyMeds; cheapest semaglutide of the three: OrderlyMeds ($149).

Every winner above is a computation, not a placement; the pairwise pages carry the full duels: ShedRx vs SkinnyRx · ShedRx vs OrderlyMeds · SkinnyRx vs OrderlyMeds.

§ Structure, three ways

Everything besides the three prices

Memberships: ShedRx none; SkinnyRx none; OrderlyMeds none. Structures: ShedRx step/tiered; SkinnyRx dose-flat; OrderlyMeds dose-flat. Pharmacies: ShedRx not named; SkinnyRx not named; OrderlyMeds not named. States: ShedRx — not published; SkinnyRx — not published; OrderlyMeds — not published. Exit terms: ShedRx — 72-hour notice before the next billing cycle; SkinnyRx — no membership on compounded programs; OrderlyMeds — not published.

The census reading: where all three match on an axis, that axis cannot break the tie and the price column rules; where they split — a membership here, an unnamed pharmacy there — the split is usually worth more than a small price gap, because structure is what you live with after month one. Evidence for all three: ShedRx source-verified (2026-08-05); SkinnyRx source-verified (2026-08-05); OrderlyMeds no public price (2026-08-05).

The trio on semaglutide, across time

3 mo: OrderlyMeds $447 vs SkinnyRx $597 vs ShedRx $747 6 mo: OrderlyMeds $894 vs SkinnyRx $1,194 vs ShedRx $1,494 12 mo: OrderlyMeds $1,788 vs SkinnyRx $2,388 vs ShedRx $2,988 — monthly-billed totals; prepaid paths where published appear on each provider page.

§ Twelve and twenty-four months

The trio, annualized

ShedRx: $3,468/yr monthly-billed; SkinnyRx: $3,588/yr monthly-billed; OrderlyMeds: $3,588/yr monthly-billed. Across two years at monthly billing the first-to-last spread widens to $240 — the horizon at which structure (prepaid ladders, flat pricing, membership drag) matters more than the sticker.

The elimination read

A three-way choice is really two eliminations, so run them in order. Eliminate OrderlyMeds first unless it names its edge: at $299 it carries a $10/month premium over the floor of this trio — $120 a year, about 0.4 extra months of therapy at ShedRx’s rate — and a premium that size must point at a specific line in its record (its particular program design) or it is decoration. Then interrogate SkinnyRx’s middle ground: its dose-flat structure removes titration repricing; if that specific thing is on your personal ledger, the $10/month over the floor can be rational — if not, the middle is where budgets go to leak. What survives is ShedRx at $289, which wins by default rather than by argument — exactly how a price index should crown things — subject to the two checks no ranking can run for you: your state at intake, and your prescriber on the medication itself.

The same trio on best published rate: ShedRx $289 → SkinnyRx $299 → OrderlyMeds $299 — all three price month-to-month only at capture. Short-horizon totals, monthly-billed: 3 months — ShedRx $867, SkinnyRx $897, OrderlyMeds $897; 6 months — ShedRx $1,734, SkinnyRx $1,794, OrderlyMeds $1,794. 0 of the three publish a prepaid path below their own monthly billing; the twelve- and twenty-four-month table below carries those, labeled.

The record-quality read, scored on the five checkable disclosures this index tracks (maintenance price, named pharmacy, published states, published cancellation terms, source-verified capture): ShedRx 4/5, SkinnyRx 4/5, OrderlyMeds 3/5. ShedRx discloses the most and OrderlyMeds the least, and in this market disclosure predicts disclosure — the axis where a program goes quiet is reliably where its checkout surprises live. The three match on every disclosure axis, which is rare and worth noting in their favor collectively. Scores recompute from the public records like everything else here.

Read as a decision: start from ShedRx and make the other two argue upward. SkinnyRx’s case is its structure; OrderlyMeds’s case must be worth $120 a year in named features — the honest unit being months of medication (0.4 of them at the floor rate). The pairwise pages above hold each argument in full, and the calculator holds your version of it.