How much cheaper is compounded semaglutide than Wegovy?

Less than it used to be. Wegovy's cash price via NovoCare↗ is $349 a month standard ($199 intro on starter doses); the cheapest verified compounded programs run $133–$165. That is a gap of roughly $184–$216 a month — about $2,436 a year at the Yucca comparison — versus the several-hundred-dollar monthly gaps of 2024. Our full comparison weighs what the difference buys.

Updated 2026-08-10 · figures captured 2026-08-09 · how we verify

The market this answer lives in, at the 2026-08-09 capture: verified compounded semaglutide runs $133–$348 a month all-in across 20 programs, with the floor at Oak Longevity (dose-flat, no membership); the approved-product benchmark is Wegovy (NovoCare) at $349 maintenance, with the oral pill from $149; and any real insurance coverage beats every cash figure named anywhere on this page.

How to use figures like these well: treat any advertised price without a maintenance-dose figure as a starter teaser; fold every mandatory membership into the total before comparing; read prepaid rates as commitments, not monthly prices; and check the capture date, because a GLP-1 price without a date is a rumor. Those four habits, applied consistently, are most of what separates this database from the marketing it indexes — the full basis definition is in the methodology, and the sortable field is in the price database.

The wider board this answer sits on: verified compounded floors of $215 (tirzepatide) and $133 (semaglutide), brand direct channels at $449 and $349 with the oral pill from $149, and insurance — where it exists — beating all of it. Prices here have only fallen for three straight years, which quietly argues for short commitments and periodic re-shopping; the price-history analysis makes that case with dates.

Basis for every figure: all-in monthly price (medication + mandatory fees) at the maintenance dose, captured from provider pages on the dates in the database. Not medical advice.